Assessing RET/PTC in thyroid nodule fine-needle aspirates: the FISH point of view
نویسندگان
چکیده
منابع مشابه
Assessing RET/PTC in thyroid nodule fine-needle aspirates: the FISH point of view.
RET/PTC rearrangement and BRAF(V600E) mutation are the two prevalent molecular alterations associated with papillary thyroid carcinoma (PTC), and their identification is increasingly being used as an adjunct to cytology in diagnosing PTC. However, there are caveats associated with the use of the molecular approach in fine-needle aspiration (FNA), particularly for RET/PTC, that should be taken i...
متن کاملMolecular Markers in Fine Needle Aspirates of the Thyroid
When Policy Topic is covered The use of the Afirma Gene Expression Classifier in fine needle aspirates of the thyroid that are cytologically considered to be indeterminate (follicular lesion of undetermined significance or follicular neoplasm) may be considered medically necessary in patients who have the following characteristics: Thyroid nodules without strong clinical or radiologic finding...
متن کاملMolecular Markers in Fine Needle Aspirates of the Thyroid
Benefit determinations are based on the applicable contract language in effect at the time the services were rendered. Exclusions, limitations or exceptions may apply. Benefits may vary based on contract, and individual member benefits must be verified. Wellmark determines medical necessity only if the benefit exists and no contract exclusions are applicable. This medical policy may not apply t...
متن کاملMicroarray analysis of thyroid nodule fine-needle aspirates accurately classifies benign and malignant lesions.
Current preoperative diagnostic procedures for thyroid nodules rely mainly on the cytological interpretation of fine-needle aspirates (FNAs). DNA microarray analysis has been shown to reliably distinguish benign and malignant thyroid nodules in surgically resected specimens, but its diagnostic potential in thyroid FNA has not been examined. In the present study, the expression profiles of 50 be...
متن کاملAssessment of the effectiveness of local anesthesia before thyroid fine needle biopsy considering the size of the nodule
Background: Fine needle aspiration biopsy (FNAB) is usually used to distinguish the malignant and benign nodules. Applying a biopsy needle evokes a sense of fear and pain in the patients. Although some studies refute the usefulness of local anesthesia (LA) prior to fine needle aspiration biopsy, it is still debatable. This prospective cross-sectional study intended to evaluate the effect of LA ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2013
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-13-0157